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translational control
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prof. Toru Shimizu
Person without affiliation with CUNI
25 publications
Publications
publication
Elucidation of the heme binding site of heme-regulated eukaryotic initiation factor 2 alpha kinase and the role of the regulatory motif in heme sensing by spectroscopic and catalytic studies of mutant proteins
2008 |
Faculty of Science, Central Library of Charles University
publication
Is ATP the Only Nucleoside Triphosphate among ATP, CTP, GTP, and UTP to Have a Role in Kinase Catalysis of Heme-Regulated Inhibitor toward eIF2 alpha during Lung Cancer Development?
2023 |
Faculty of Science, Central Library of Charles University
publication
Hydrogen/deuterium exchange mass spectrometry of heme-based oxygen sensor proteins
2023 |
Faculty of Science, Central Library of Charles University
publication
Is ATP the Only Nucleoside Triphosphate among ATP, CTP, GTP, and UTP to Have a Role in Kinase Catalysis of Heme-Regulated Inhibitor toward eIF2α during Lung Cancer Development?
2023 |
Faculty of Science
publication
Characterization of the interaction between the tumour suppressor p53 and heme and its role in the protein conformational dynamics studied by various spectroscopic techniques and hydrogen/deuterium exchange coupled with mass spectrometry
2023 |
Faculty of Science
publication
Monitoring the Kinase Activity of Heme-Based Oxygen Sensors and Its Dependence on O2 and Other Ligands Using Phos-Tag Electrophoresis
2023 |
Faculty of Science
publication
Signal transduction mechanisms in heme-based globin-coupled oxygen sensors with a focus on a histidine kinase (AfGcHK) and a diguanylate cyclase (YddV or EcDosC)
2022 |
Faculty of Science
publication
Disruption of the dimerization interface of the sensing domain in the dimeric heme-based oxygen sensor AfGcHK abolishes bacterial signal transduction
2020 |
Faculty of Science
publication
Kinetic analysis of a globin-coupled diguanylate cyclase, YddV: Effects of heme iron redox state, axial ligands, and heme distal mutations on catalysis
2019 |
Faculty of Science
publication
Heme: Emergent roles of heme in signal transduction, functional regulation and as catalytic centres
2019 |
Faculty of Science
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