The pregnancies of women showing both significant titers of the specific acute antibodies against T.gondii and IgG class titers should be followed both during pre- and post-natal period. However, if the infection of the fetus is not proven prenatally, the newborn shows normal ultrasound of the brain, decrease of the specific IgG antibody titers and is PCR negative for the T.gondii, DNA, the diagnosis of congenital toxoplasmosis is highly unlikely.