Azathioprine versus mesalazine for prevention of postoperative clinical recurrence in patients with Crohn's disease with endoscopic recurrence: efficacy and safety results of a randomised, double-blind, double-dummy, multicentre trial
2010
Abstract
The aim of the study was to compare azathioprine versus mesalazine for the prevention of clinical recurrence in patients with postoperative Crohn's disease with moderate or severe endoscopic recurrence. Clinical recurrence was significantly less frequent with azathioprine versus mesalazine, whereas study drug discontinuation due to adverse drug reactions only occurred in azathioprine-treated patients. 10.1136/gut.2009.194159