The full-term newborn passes first stool after birth of the characteristic appearance called meconium. This mixture of epithelial cells and products of the intestinal glands has a brownish black color significantly thick and viscous.
Under normal circumstances, the majority of newborn pass meconium during the first 24 hours. Disorders of the meconium discharge may occur as the meconium ileus or of the meconium plugs syndrome.
In both cases, intestinal obstruction is caused by an abnormally thickened meconium adhering to the intestinal wall. When meconium ileus occurred, moconium is usually in the distal ileum, distally there is a microcolon and there is in most cases associated with cystic fibrosis.