alpha5beta1 integrin antagonists reduce chemotherapy-induced premature senescence and facilitate apoptosis in human glioblastoma cells.

Abstract

The paper describes that alpha5beta1 integrin antagonists reduce chemotherapy-induced premature senescence and facilitate apoptosis in human glioblastoma cells.

Keywords

• a5b1 integrin
• antagonists
• ellipticine
• temozolomide
• human glioblastoma
• senescence
• apoptosis
• chemotherapy
• p53