Mechanisms of the different DNA adduct forming potentials of the urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone

Abstract

The paper describes mechanisms of the different DNA adduct forming potentials of the urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone.

Keywords

• environmental contaminant 3-nitrobenzanthrone
• anticancer drug ellipticine
• diesel exhaust
• nad(p)h-quinone oxidoreductase-1
• intratracheal instillation
• metabolic-activation
• human hepatocytes
• solvation model
• ionic solutes
• ab-initio