Aplastic Anemia as a Cause of Death in a Patient with Glioblastoma Multiforme Treated with Temozolomide

Abstract

The authors present the case of a 61-year-old female patient with glioblastoma multiforme treated with external-beam radiation therapy and concomitant temozolomide. After completion of treatment, the patient developed symptoms of serious plastic anemia that evetually led to death due to prolonged neutro-and thrombocytopenia followed by infectious complications.

Keywords

• Glioblastoma multiforme
• temozolomide
• aplastic anemia