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Plasma interleukin-6 level is associated with NT-PROBNP level and predicts short- and long term moratlity in patients with acute heart failure

Publication at Faculty of Medicine in Hradec Králové |
2010

Abstract

The study analyses plasma interleukin 6 and natriureticc peptide (NT-proBNP) level in 92 pacients with acute heart failure. In multivariate analysis, increased plasma IL-6 and NT-proBNP levels remained strong independent predictors of 1-year mortality.

Plasma IL-6 levels provide important prognostic information in the patients with ADHF. Measurement combining plasma IL-6 and NT-proBNP should serve as a powerful prognostic tool of multimarker strategy in patients with acute decompensated heart failure.