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Enhanced capabilities of separation in Sequential Injection Chromatography - Fused-core particle column and its comparison with narrow-bore monolithic column

Publication at Faculty of Pharmacy in Hradec Králové |
2011

Abstract

This article presents the first use of fused-core particle packed column in an attempt to extend of the chromatographic capabilities of the SIC system. The system was tested by the separation of four estrogens with similar structure and an internal standard - ethylparaben.

Obtained results and conclusions have shown that both fused-core particle column and longer narrow shaped monolithic column bring benefits into the SIC method.