Acetylcholinesterase and Butyrylcholinesterase Inhibitory Compounds from Corydalis cava (Fumariaceae)

Abstract

From the tubers of Corydalis cava have been isolated 15 isoquinoline alkaloids. All compounds were tested for their acetylcholinesterase and butyrylcholinesterase inhibition activity.

The best activities have been demonstrated by canadaline, canadine and corycavidine. Other isolated compounds were considered inactive.

Keywords

• Corydalis cava
• Fumariaceae
• Alzheimer's disease
• red blood cells
• acetylcholinesterase
• butyrylcholinesterase