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Complex modulation of peptidolytic activity of cathepsin D by sphingolipids

Publication at Faculty of Science, Faculty of Pharmacy in Hradec Králové |
2011

Abstract

A complex pattern of modulation of the peptidolytic activity of cathepsin D by sphingolipids was described. Sphingolipids and phosphosphingolipids, known to be antagonistic in their cell signalling functions, displayed opposite modulation of cathepsin D.