Decreased level of psychobiological factor Novelty seeking and lower intelligence in men latently infected with protozoan parasite Toxoplasma gondii.
Abstract
Toxoplasma gondii, a parasitic protozoan, infects about 30-60% of people worldwide. The latent toxoplasmosis, i.e. life-long presence of cysts in the brain and muscular tissues, has no effect on human health.
However, infected subjects score worse in psychomotor performance tests and have different personality profiles than Toxoplasma-negative subjects. The mechanism of this effect is unknown; however, it is supposed that presence of parasites cysts in the brain induces an increase of the concentration of dopamine.
Here we search for the existence of differences in personality profile between Toxoplasma-positive and Toxoplasmanegative subjects by testing 857 military conscripts using a modern psychobiological questionnaire, namely with Cloningers Temperament and Character Inventory (TCI). ANCOVA showed that Toxoplasma-positive subjects had lower Novelty seeking (NS) scores P/0.035) and lower scores for three of its four subscales, namely Impulsiveness (P=0.049), Extravagance (P=0.056) and Disorderlin