Synthesis of oligoribonucleotides with phosphonate-modified linkages

Abstrakt

Solid phase synthesis of phosphonate oligoribonucleotides using 2-O-benzoyloxymethoxymethyl protected monomers is presented in both 3-5 and 5-3 directions.

Klíčová slova

• oligoribonucleotide
• phosphonate
• modified RNA