Publication at Faculty of Medicine in Hradec Králové |
2008
Abstract
Paliperidone tablets with extended release is a new antipsychotic drug registered for the treatment of schizophrenia. Paliperidone 9 hydroxy risperidone is an active metabolite of risperidone.
The OROS (osmotic controlled-release oral delivery system) technology provides extended release of active substance and relatively stabile plasmatic level of the drug. Clinical efficacy is comparable with risperidone.
Paliperidone ER tablets are well tolerated and have simple dosage regimen.