The aim of our study was to analyze our results of the surgical therapy at a center which performs approximately 15 resections and 20 other procedures on pancreas a year.A group of patients with pancreatic resection operated on at the Department of Surgery, University Hospital in Hradec Králové between 1996 and 2006 was analyzed retrospectively. 158 pancreatic resections were performed in the referred period, 116 partial duodenopancreatectomies,1 total duodenopancreatectomy and 41 distal resections of pancreas.Our results of surgical therapy are comparable with the results of other hospitals with similar frequency of the pancreas resection,regarding postoperative mortality and morbidity,also regarding long-term results.