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News in therapy and prevention of venous thromboembolism

Publication at Faculty of Medicine in Hradec Králové |
2008

Abstract

New drugs in therapy and prevention of thromboembolic disease are direct and non direct thrombin inhibitors, and inhibitors of F Xa. Inhibition of thrombin and Factor Xa prevents thrombin generation rather than blocking thrombin itself, resulting in a sustained attenuation of thrombotic activity.