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Abnormal hyperbilirubinemia in a patient with multiple myeloma

Publication at Faculty of Medicine in Hradec Králové |
2008

Abstract

Falsely elevated serum bilirubin in patient with multiple myeloma. We determined serum bilirubin in patient with multiple myeloma by using Modular and we repeated analysis by using Olympus 400.

Concentration of IgG kappa was 61,6 g/l. Serum bilirubin value measured on the Modular Roche has been 546 micromole/l, while repeated measurement on Olympus 400 provided value only 6 micromole/l.

Lower Olympus value corresponded to clinical status of the patient. We found extremely high systematic error in presence IgG kappa only in Modular Roche, not in Olympus 400