Pityriasis Lichenoides et Varioliformis Acuta With Numerous CD30+ Cells: A Variant Mimicking Lymphomatoid Papulosis and Other Cutaneous Lymphomas. A Clinicopathologic, Immunohistochemical, and Molecular Biological Study of 13 Cases

Abstract

Pityriasis lichenoides comprises a clinicopathologic spectrum of cutaneous inflammatory disorders, with the 2 most common variants being pityriasis lichenoides et varioliformis acuta (PLEVA) and pityriasis lichenoides chronica. The aim of the study was to describe 13 cases of a unique PLEVA variant characterized in the conspicuous CD30+ component and thus mimicking lymphomatoid papulosis (LyP), a condition currently classified in the spectrum of CD30+ lymphoproliferative disorders.

Keywords

• cutaneous lymphoma
• CD30
• lymphomatoid papulosis
• pityriasis lichenoides
• parvovirus B19