Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Eschscholzia californica (Papaveraceae)

Abstrakt

Fourteen compounds have been isolated from the roots and aerial parts of Eschscholzia californica (Papaveraceae). All isolated alkaloids were tested for their cholinesterase (AChE, BuChE) inhibitory activity.

Klíčová slova

• Eschscholzia californica
• Papaveraceae
• isoquinoline alkaloids
• Alzheimer&apos
• s disease
• red blood cells
• acetylcholinesterase
• butyrylcholinesterase
• reticuline
• 1-(3-hydroxy-4-methoxybenzyl)-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline