3,5-Disubstituted pyranone analogues of highly antifungally active furanones: Conversion of biological effect from antifungal to cytostatic

Abstrakt

A series of 3-aryl-5-acyloxymethyl-5,6-dihydropyran-2-ones related to 3,5-disubstituted furanones with high antifungal effect was prepared, and the compounds evaluated for antifungal and cytostatic activity.

Klíčová slova

• pyranone
• synthesis
• screening
• antifungal
• cytostatic