New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase

Abstrakt

In the paper, we describe novel HPLC method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase in cell culture media and lysates.

Klíčová slova

• high-performance liquid chromatography
• chiral separation
• macrocyclic glycopeptides
• (R)-warfarin
• (S)-warfarin