Dexamethasone and betamethasone administration during pregnancy affects expression and function of 11beta-hydroxysteroid dehydrogenase type 2 in the rat placenta

Abstrakt

The effect of two commonly used synthetic steroids, dexamethasone and betamethasone, on the expression and function of 11beta-HSD2 in the rat placenta was investigated with respect to fetoprotective activity.

Klíčová slova

• 11beta-hydroxysteroid dehydrogenase
• metabolism
• rat placenta
• dexamethasone
• betamethasone