Computational and chromatographic study of hydrophobic properties of hydroxylated 3-phenyl-1-pyrazin-2-ylpropen-1-ones
Abstract
RM values obtained in a RP-TLC study were compared with logP values calculated by various commercially available programmes; the RM values correlated well with van der Waals volumes and hydration energies derived of molecular models on RHF/AM1 level [g0018]