Dicrocoeliosis of old mouflon ewes - effect on biotransformation enzymes and metabolism of anthelmintics in vitro

Abstract

Dicrocoeliosis in mouflons caused only mild changes in ABZ and FLU hepatic biotransformation, but activities of glutathione-S-transferase and UDP-glukuronosyltransferase were significantly decreased in infected mouflons

Keywords

• Dicrocoelium dendriticum
• lancet fluke
• albendazole
• flubendazole
• drug metabolism