1-hydroxy-1,1-bis(H-phosphinates): Synthesis, stability, and sorption properties

Abstrakt

A synthesis of 1-hydroxy-1,1-bis(H-phosphinates) from acylchlorides is described. Solid-state structures of two bis(phosphinates) determined by X-ray diffraction showed variations in the P-C distances.

The compounds show negligible sorption on hydroxyapatite and an intermediate chemical stability in aqueous solution. The hydrolysis occurs in acidic as well as alkaline media.

Hydrolysis rates of four derivatives show the lowest stability for aromatic derivatives as a result of the electron-withdrawing effect. Main products of hydrolysis are 1-hydroxy-(H-phosphinates) and phosphorous acid.

Klíčová slova

• bis(phosphinates)
• phosphinic acid
• hydrolytical stability
• organophosphorus synthesis