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Preparation of Quinolinium Salts Differing in the Length of the Alkyl Side Chain

Publication |
2012

Abstract

Quaternary quinolinium salts differing in alkyl chain length are members of a widespread group of cationic surfactants. These compounds have numerous applications in various branches of industry and research.

In this work, the preparation of quinoline-derived cationic surface active agents differing in the length of the side alkyl chains (from C-8 to C-20) is described. An HPLC method was successfully developed for distinction of all members of the series of prepared long-chain quinolinium derivatives.

In conclusion, some possibilities of intended tests or usage have been summarized. In vitro testing using a microdilution broth method showed good activity of a substance with a C12 chain length against Gram-positive cocci and Candida species.