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Evaluation of the potential aditivity and interactions in mixtures of chemical substances in the working atmosphere

Publication at Faculty of Medicine in Hradec Králové |
2012

Abstract

Exposure to mixtures of substances can induce biological interactions that significantly affect the final response of the organism. The Czech version of the database "miXie" presented in this publication, increases the reliability of an estimate of the additive and interaction potential of any mixture of substances (additivity, supra-additivity, infra-additivity), and can facilitate decision-making processes in the field of occupational hygiene, industrial toxicology and occupational medicine.