Treatment of peptic ulcers depends on the aetiology and clinical presentation (presence or absence of complication, recurrent or refractory ulcer). The initial management of a stable patient with dyspepsia differs from the therapy of an unstable patient with upper gastrointestinal haemorrhage.
Nowadays conservative therapy dominates (the goal is to suppress production of hydrochloric acid and to eradicate possible Helicobacter pylori infection). Surgery is indicated in severe complications only.
Bleeding peptic ulcer is controlled by endoscopy in most cases (or by invasive radiology or surgery in case of failure of endoscopy).