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NOPO, a novel bifunctional and highly selective chelator for Gallium-68

Publication

Abstract

Triazacyclononane-based ligand with one 2-carboxyethylphosphinic and two hydroxomethylphosphinic acid pendant arms was synthesized and conjugated with physiologically active peptides through the carboxylate moiety. 68-Ga complexes with that ligands were prepared and their in vivo behaviour was investigated.