Publication at Faculty of Medicine in Hradec Králové |
2011
Abstract
Systemic treatment of metastatic colorectal cancer has become an irreplaceable part of the treatment strategy. The livers is the most common site of distant metastasis.
Induction systemic therapy is indicated in patients with potentially operable metastatic disease. When in a good performance status, patients with distant unresectable metastasis should be treated with combination chemotherapy and targeted therapy.
The regimens combining fluoropyrimidine, oxaliplatin, irinotecan, bevacizumab, cetuximab and panitumumab have found the widest use.