High doses of rotigotine transdermal patch: results of an open-label, dose-escalation trial in patients with advanced-stage, idiopathic Parkinson disease

Abstract

The objective of the study was to determine the maximal achievable dose of rotigotine by assessing the tolerability of escalating doses of rotigotine transdermal patch in patients with advanced-stage Parkinson disease.

Keywords

• dopamine agonist
• dose escalation
• maximal achievable dose
• Parkinson disease
• rotigotine transdermal patch