The metastasis promoting protein S100A4 is increased in idiopathic inflammatory myopathies

Abstract

The S100A4 protein is known as a metastasis promoting factor; however, its involvement in non-malignant diseases such as RA and psoriasis has been recently described. The aim of this study was to investigate the expression and possible role of S100A4 in idiopathic inflammatory myopathies.

Keywords

• S100A4
• Polymyositis
• Dermatomyositis
• Peripheral blood mononuclear cells
• Myocytes
• Inflammation