Pregnancy outcome in inflammatory bowel disease: prospective European case-control ECCO-EpiCom study, 2003–2006
Abstract
Inflammatory bowel disease (IBD) frequently affects women during their reproductive years. The aim of the study was to evaluate the pregnancy outcome in patients with IBD in a prospective European multicentre case-control study.
Inflammatory bowel disease pregnant women from 12 European countries were enrolled between January 2003 and December 2006 and matched (1:1) to non-IBD pregnant controls by age at conception and number of previous pregnancies. A total of 332 pregnant women with IBD were included: 145 with Crohn’s disease (CD) and 187 with ulcerative colitis (UC).
No statistically significant differences in frequency of abortions, preterm deliveries, caesarean sections, congenital abnormalities and birth weight were observed comparing CD and UC women with their non-IBD controls.