Genetic locus on rat chromosome 20 regulates diet-induced adipocyte hypertrophy: a microarray gene expression study

Abstract

Annotation: We have shown that a specific segment of rat chromosome 20 (RNO20) contains a gene(s) regulating the degree of obesity, glukose intolerance and hypertension in response to a chronic high-fat diet (HFD). W examined microarraygene-expression profiles and cellular morphology of adipose tissues and whole-body energy expenditure .

Keywords

• obesity
• genetics
• microarray gene expression profiling