Publication at First Faculty of Medicine |
2009
Abstract
Hemolytic disease of the newborn causes severe fetal and neonatal mortality and morbidity. Highest risk of alloimmunization is in connection with delivery/labour and/or intrauterine invasive procedures during pregnancy.
Alloimmunization of Rh-D negative mothers can be prevented in most cases with administration of anti-D imunoglobulin. Today we have no effective treatment for women where alloimmunization has already developed.
Alloimmunization can prevent the women from further reproduction. This paper presents guidelines for anti-D administration in pregnancy.