Aim of the study is to determine whether narrow band imaging (NBI) improves detection of non-muscle-invasive bladder cancer over white-light imaging (WLI)cystoscopy. It is a prospective study with 103 consecutive procedures on 95 patients scheduled for (re-) transurethral resection of a bladder tumor (84) or bladder biopsies (19), WLI and NBI cystoscopy were subsequently performed by different surgeons who independently indicated all tumors and suspect areas on a bladder diagram.The lesions identified were resected/biopsied and sent for histopathological examination.
The detection rate of NBI was 94.7% VS 79.2% FOR WLI(P<.001). The false-positive rate of NBI and WLI was 31.6% and 24.5%, respectively (P<.001).Authors concluded that NBI cystoscopy improves the detection of primary and recurrent nonmuscle invasive bladder cancer over WLI.