Development and Initial Validation of Composite Parent- and Child-Centered Disease Assessment Indices for Juvenile Idiopathic Arthritis
2011
Abstract
Newly developed parent- (JAPAI) and child-centered (JACAI) disease assessment indices include 4 measures: rating of overall well-being, pain, physical function, and health-related quality of life. Validation process included assessment of construct validity, discriminant validity, responsiveness to change, and reliability.
Both indices were found to be valid instruments for assessment of disease status in JIA and suitable surrogates of physicians' evaluations. They are potentially applicable in clinical practice, observational studies, and therapeutic trials.