Novel therapeutic targets in non-small cell lung cancer

Abstrakt

This review describes molecular targets in non-small cell lung cancer that are in development or being clinically applied and their implications for developing novel anticancer therapies for this previously refractory malignancy.

Klíčová slova

• Non-small cell lung cancer
• molecular target
• mutation
• EGFR
• VEGF
• VEGFR
• KRAS
• BRAF
• PIK3CA
• EML4-ALK
• IGF-1R