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Autologous Hematopoietic Stem Cells Transplantation and its Current Role in Multiple Sclerosis Treatment

Publication at First Faculty of Medicine, Third Faculty of Medicine |
2009

Abstract

Multiple sclerosis (MS) is the most frequent autoimmune disorder of the central nervous system in our geographical region. The disease can lead to variable degree of neurological disability according to aggressiveness of MS course itself, early treatment initiation and its invidividual efficacy.

In about 3% of the patients MS course can be classified as malignant with severe attacks from the beginning of the disease and rapid accumulation of neurological disability despite adequate treatment.