Proportions of immature CD19+CD21- B lymphocytes predict the response to extracorporeal photopheresis in patients with chronic graft-versus-host disease

Abstract

In this pilot study, a higher percentage of immature B-cells was a significant predictor of therapeutic failure of extracorporeal photopheresis. Our findings warrant larger prospective studies analyzing the predictive value of B-cell subsets for successful ECP treatment of cGVHD.

Keywords

• alloHSCT
• chronic GVHD
• ECP
• immature B-lymphocytes