Adalimumab fot the treatment of perianal fistulas in patients with Crohn's disease. Commented report on the post hoc analysis of the CHARM and ADHERE studies.

Abstract

The management of fistulizing Crohn's disease, especially in perineal area, is among the major problems in the clinical practice. The authors address the recently published post hoc analysis of the CHARM and AdHERE studies of a) adalimumab in Crohn's disease perianal fistulas and b)a novel and (probably) more accurate method is available for evaluating the efficacy of a therapy in the healing of perianal fistulas.

Keywords

• adalimumab
• Crohn's disease
• perianal fistulas