Transkribovaná DNA je přednostně lokalizována v perichromatické oblasti jádra savčích buněk

Abstrakt

In cooperation with the University in Lausanne, high-resolution distribution of in-situ hybridization signal co-localizing with both transcriptionally active genes and their polyadenylated RNA sequence was analyzed. It was demonstrated that these genes are localized particularly in perichromatin area where transcription takes place.

Klíčová slova

• Transcribed DNA
• Nuclear architecture
• Ultrastructural
• In situ hybridization
• Perichromatin region