What is the significance of cerebrospinal fluid examination in the light of new diagnostic criteria for multiple sclerosis
2012
Abstract
Cerebrospinal fluid examination is among the basic diagnostic criteria for establishing the diagnosis of multiple sclerosis. The diagnosis rests on the demonstration of oligoclonal immunoglobulins or intrathecal immunoglobulin synthesis.
Cerebrospinal fluid collection should be pereformed by using a atraumatic needle to reduce post-puncture complaints. Cerebrospinal fluid examination is of differential diagnostic significance.
In order to determine the prognosis of the cognition, an effort must be made to fund optimal markers. The algorithm of examination is based on clinical recommendations.
The article aims to provide coherent information on the options of cerebrospinal fluid diagnosis in multiple sclerosis