The clinical importance of a genetic analysis of moderate-risk cancer susceptibility genes in breast and other cancer patients from the Czech Republic

Abstract

We have performed mutation analyses of moderate-risk cancer susceptibility genes to evaluate their clinical importance for genetic counseling in high-risk patients suffering from breast and other cancers in the Czech population.

Keywords

• hereditary cancer
• genetic testing
• ATM
• CHEK2
• NBS1 (NBN)
• PALB2