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Possibility to study low-dose biodosimetry.

Publication

Abstract

At the present time exists a number of laboratory techniques to determine the degree of effect of low doses of ionizing radiation. Exposure to ionizing radiation is documented by chromosomal aberrations (eg dicentromeres), but the half-life of their elimination from a circulating blood is approximately 3 years.

Stable chromosomal aberrations (translocations, deletions) are much more visible and can be identified even decades after exposure. It's analysis is much more complex by FISCH laboratory method.

An alternative method of detecting chromosomal aberrations seems to be the determination of the number of micronuclei in lymphocytes.