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Biochemical oxidative stress-related markers in patients with obstructive sleep apnea

Publication at First Faculty of Medicine |
2011

Abstract

Obstructive sleep apnea (OSA) is a condition contributing to oxidative stress. The aim of this study was to ascertain if there is any connection between OSA and novel oxidative stress-related markers.

We found positive correlation of ODI and SpO2 30 independent of BMI. Conclusions: MMP-9, hsCRP, sRAGE and Cu seem to be strong predictors of oxidative stress in OSA patients.

The strong correlation between oxidative stress-related markers and OSA is elucidated by connection of these to BMI, which is probably a primary condition of oxidative stress, but OSA is an additive condition.