Lysosomal compromise and brain dysfunction: examining the role of neuroaxonal dystrophy

Abstract

The article proposes roles of neuroaxonal dystrophy (NAD) in the molecular and cellular pathogenesis of lysosomal storage disorders. It focuses on the impact of NAD on Purkinje cells sustenance.

Keywords

• Lysosomal storage disorders
• neuroaxonal dystrophy
• Purkinje cells