A pre-morbid 'baseline' creatinine is required in order to diagnose and stage acute kidney injury (AKI) using the RIFLE classification. We analysed the performance of 3 methods to estimate baseline creatinine in four cohorts of intensive care unit patients.
Using any of the three methods, the median absolute error of the estimates was of the order of 0.1–0.2 mg/dl, and overall accuracy was similar.