Pheochromocytomas and functional paragangliomas are catecholamine-producing tumors which present mostly with headache, sweating, palpitations, and hypertension. Biochemical testing for pheochromocytoma is mandatory not only in subjects with clinical suspicion for pheochromocytoma but also in subjects with incidentally discovered adrenal mass or in subjects with genetic predisposition.
Computed tomography, magnetic resonance imaging and functional imaging with [123I]-metaiodobenzylguanidine may be used for tumor localization. Medical pre-treatment is essential for successful operation which is performed in most cases by minimal invasive surgery.
After tumor removal, further follow-up is necessary due to possible recurrence.