Abstract
Secondary dyslipidaemia (DLP) whose frequency ranged between 30 – 40 % of all DLP is consequence of a number of disease - liver disease and biliary obstruction, renal diseases, anorexia nervosa, hormonal disorders (hypothyroidism, androgen deficiency, acromegaly, diabetes mellitus, pregnancy, eostrogens as contraceptive or replacement therapy, hypercorticalism), infectious disease, inflammation, malnutrition). Some secondary DLP are connected with ethanol abuse, or are caused by xenobiotics (beta-blockers, thiazide diuretics, retinoids, corticosterids, immunosuppressants, dioxins, chlorinated hydrocarbons, etc.).
Although many of disorders above mentioned can cause DLP in their own right it is apparent that the most marked lipid and lipoproteinb abnormalities tend to occur in those individuals that have a genetic predisposition. It is stated the overview, pathophysiology, clinical manifestation, laboratory findings, as well as management of secondary dyslipidaemias.